Nanopore technology: Difference between revisions
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= Nanopore technology = | = Nanopore technology = <!--T:1--> | ||
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'''Nanopore technology''' uses nanoscale pores to observe molecules through changes in electrical current, ion flow, or related measurable signals. A nanopore can be biological, such as a protein pore embedded in a membrane, or solid-state, fabricated from materials such as silicon nitride or graphene. | '''Nanopore technology''' uses nanoscale pores to observe molecules through changes in electrical current, ion flow, or related measurable signals. A nanopore can be biological, such as a protein pore embedded in a membrane, or solid-state, fabricated from materials such as silicon nitride or graphene. | ||
== Core idea == | == Core idea == <!--T:3--> | ||
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When a molecule passes through or interacts with a nanopore, it partially blocks or modifies the signal across the pore. The resulting signal pattern can provide information about molecular size, charge, structure, sequence, or binding behavior. | When a molecule passes through or interacts with a nanopore, it partially blocks or modifies the signal across the pore. The resulting signal pattern can provide information about molecular size, charge, structure, sequence, or binding behavior. | ||
== Major directions == | == Major directions == <!--T:5--> | ||
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* [[Nanopore sequencing]] for DNA and RNA analysis. | * [[Nanopore sequencing]] for DNA and RNA analysis. | ||
* [[Single-molecule detection]] for proteins, peptides, small molecules, and biomarkers. | * [[Single-molecule detection]] for proteins, peptides, small molecules, and biomarkers. | ||
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* Long-read genomics and real-time data analysis workflows. | * Long-read genomics and real-time data analysis workflows. | ||
== Related pages == | == Related pages == <!--T:7--> | ||
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* [[Nanopore sequencing]] | * [[Nanopore sequencing]] | ||
* [[Single-molecule detection]] | * [[Single-molecule detection]] | ||
Revision as of 22:38, 28 June 2026
Nanopore technology
Nanopore technology uses nanoscale pores to observe molecules through changes in electrical current, ion flow, or related measurable signals. A nanopore can be biological, such as a protein pore embedded in a membrane, or solid-state, fabricated from materials such as silicon nitride or graphene.
Core idea
When a molecule passes through or interacts with a nanopore, it partially blocks or modifies the signal across the pore. The resulting signal pattern can provide information about molecular size, charge, structure, sequence, or binding behavior.
Major directions
- Nanopore sequencing for DNA and RNA analysis.
- Single-molecule detection for proteins, peptides, small molecules, and biomarkers.
- Portable sensing systems for field, clinical, environmental, and food-safety use cases.
- Long-read genomics and real-time data analysis workflows.