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<div class="plainlinks">'''Languages:''' [[Nanopore technology|English]] | [[Nanopore technology/zh|中文]] | [[Nanopore technology/es|español]] | [[Nanopore technology/fr|français]] | [[Nanopore technology/de|Deutsch]] | [[Nanopore technology/ja|日本語]]</div>
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= Nanopore technology =
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= 纳米孔技术 =
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'''Nanopore technology''' uses nanoscale pores to observe molecules through changes in electrical current, ion flow, or related measurable signals. A nanopore can be biological, such as a protein pore embedded in a membrane, or solid-state, fabricated from materials such as silicon nitride or graphene.
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'''纳米孔技术''' 使用纳米级孔隙通过电流、离子流或相关可测量信号的变化来观察分子。纳米孔可以是生物性的,例如嵌入膜中的蛋白质孔,也可以是固态的,由硅氮化物或石墨烯等材料制成。
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== Core idea ==
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== 核心理念 ==
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When a molecule passes through or interacts with a nanopore, it partially blocks or modifies the signal across the pore. The resulting signal pattern can provide information about molecular size, charge, structure, sequence, or binding behavior.
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当分子通过或与纳米孔相互作用时,它会部分阻断或改变孔隙中的信号。由此产生的信号模式可以提供关于分子大小、电荷、结构、序列或结合行为的信息。
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== Major directions ==
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== 主要方向 ==
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* [[Nanopore sequencing]] for DNA and RNA analysis.
* [[Single-molecule detection]] for proteins, peptides, small molecules, and biomarkers.
* Portable sensing systems for field, clinical, environmental, and food-safety use cases.
* Long-read genomics and real-time data analysis workflows.
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* [[纳米孔测序]]用于DNA和RNA分析。
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* [[单分子检测]]用于蛋白质、肽、小分子和生物标志物的检测。
== Related pages ==
* 便携式传感系统,适用于现场、临床、环境和食品安全使用场景。
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* 长读长基因组学和实时数据分析流程。


== 相关页面 ==
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* [[Nanopore sequencing]]
* [[Single-molecule detection]]
* [[Bioinformatics]]
* [[Glossary]]
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* [[纳米孔测序]]
<languages />
* [[单分子检测]]
* [[生物信息学]]
* [[术语表]]

Revision as of 23:45, 28 June 2026

Nanopore technology

Nanopore technology uses nanoscale pores to observe molecules through changes in electrical current, ion flow, or related measurable signals. A nanopore can be biological, such as a protein pore embedded in a membrane, or solid-state, fabricated from materials such as silicon nitride or graphene.

Core idea

When a molecule passes through or interacts with a nanopore, it partially blocks or modifies the signal across the pore. The resulting signal pattern can provide information about molecular size, charge, structure, sequence, or binding behavior.

Major directions

  • Nanopore sequencing for DNA and RNA analysis.
  • Single-molecule detection for proteins, peptides, small molecules, and biomarkers.
  • Portable sensing systems for field, clinical, environmental, and food-safety use cases.
  • Long-read genomics and real-time data analysis workflows.