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__NOTOC__
__NOTOC__
<div style="border:1px solid #a2a9b1; background:#f8f9fa; padding:1.2em; margin-bottom:1em; overflow:hidden;">
<div style="border:1px solid #a2a9b1; background:#f8f9fa; padding:1.2em; margin-bottom:1em; overflow:hidden;">
[[File:Nanopore_sequencing_principle.png|thumb|right|360px|Principle of nanopore sequencing. Source: Wikimedia Commons, DBCLS, CC BY 4.0.]]
[[File:Nanopore_sequencing_principle.png|thumb|right|360px|link=https://www.nanopore.net/index.php?curid=2|???????????Wikimedia Commons?DBCLS?CC BY 4.0?]]
<div style="font-size:188%; line-height:1.2; margin-bottom:0.25em;">欢迎访问 Nanopore Wiki</div>
<div style="font-size:188%; line-height:1.2; margin-bottom:0.25em;">???? Nanopore Wiki</div>
<div style="font-size:108%; max-width:58em;">有关纳米孔技术、纳米孔测序、单分子传感、生物信息学工作流程、仪器和前沿研究的知识库和科学推广网站。</div>
<div style="font-size:108%; max-width:58em;">??????????????????????????????????????????????</div>
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</div>
???????????????????????????????????????????????????????????????????????????????????? DNA?RNA????????????????????
???????????????????????????????????? DNA ? RNA ???????????????????????????????????????????????????????????????????


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== 从这里开始 ==
== ????? ==
* [[Nanopore technology|纳米孔技术]]
* [[Nanopore technology|?????]] - ???????????????
* [[Nanopore sequencing|纳米孔测序]]
* [[Nanopore sequencing|?????]] - ?????? DNA ? RNA ???????
* [[Single-molecule detection|单分子检测]]
* [[Single-molecule detection|?????]] - ????????????
* [[Bioinformatics|生物信息学]]
* [[Bioinformatics|?????]] - basecalling???????????????????
* [[Glossary|术语表]]
* [[Glossary|???]] - ??????????


纳米孔是一种纳米级孔隙，可通过电流、离子流或其他可测量信号的变化来观察分子。这使得它们在测序、分子传感和实时分析方面非常有用。
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== ????? ==
* ?????????????????????????
* ?????????????????????????
* ???????????????????????
* ????????? RNA???????????????


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== 最新进展 ==
{{:Latest Progress}}
|-
|-
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== 研究课题 ==
== ???? ==
* [[Long-read sequencing|长读测序]]
* ??????????????
* [[Direct RNA sequencing|直接 RNA 测序]]
* ??????????
* [[Epigenetic modification detection|表观遗传修饰检测]]
* ?? DNA ????????
* [[Pathogen detection|病原体检测]]
* ???????????
* [[Environmental DNA|DNA 环境]]
* ????????????
* [[Protein nanopore sensing|蛋白质纳米孔传感]]
* ???????????RNA ???????????


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== 工具和工作流程 ==
== ????? ==
* [[MinION|MinION]]
* [[MinION]] ??????????
* [[Oxford Nanopore|牛津纳米孔]]
* [[Oxford Nanopore]] ?????????
* [[Basecalling|基地呼叫]]
* ??????????? basecalling
* [[Read mapping|阅读映射]]
* ????????????????????
* [[Variant calling|变体调用]]
* ??????????????????????
* [[Genome assembly|基因组组装]]
 
* [[Quality control|质量控制]]
|-
|-
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== 应用 ==
== ???? ==
* 公共卫生监测
{{:Latest Progress}}
* 临床和病原体基因组学
* 农业和食品安全
* 环境监测
* 微生物组和元基因组学
* 结构变异分析


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== 投稿 ==
== ???? ==
添加新页面、改进定义、总结最新论文并更新方法页面。对于新的进展项目，请编辑 [[Latest Progress|最新进展]] 这样主页就会自动更新。
Nanopore Wiki ??????????????????????????????????????????????????????????????????


== 参考资料 ==
<div lang="en" dir="ltr" class="mw-content-ltr">
* [https://en.wikipedia.org/wiki/Nanopore 纳米孔 - 维基百科]
== Site Notes ==
* [https://en.wikipedia.org/wiki/Nanopore_sequencing 纳米孔测序 - 维基百科]
Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice.
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg 纳米孔测序原理 - 维基共享资源]
</div>
 
<div lang="en" dir="ltr" class="mw-content-ltr">
== References ==
* [https://en.wikipedia.org/wiki/Nanopore Nanopore - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore_sequencing Nanopore sequencing - Wikipedia]
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg Principle of nanopore sequencing - Wikimedia Commons]
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Revision as of 12:57, 29 June 2026

???????????Wikimedia Commons?DBCLS?CC BY 4.0?
???? Nanopore Wiki
??????????????????????????????????????????????

???????????????????????????????????????????????????????????????????????????????????? DNA?RNA????????????????????

???????????????????????????????????? DNA ? RNA ???????????????????????????????????????????????????????????????????

?????

  • ????? - ???????????????
  • ????? - ?????? DNA ? RNA ???????
  • ????? - ????????????
  • ????? - basecalling???????????????????
  • ??? - ??????????

?????

  • ?????????????????????????
  • ?????????????????????????
  • ???????????????????????
  • ????????? RNA???????????????

????

  • ??????????????
  • ??????????
  • ?? DNA ????????
  • ???????????
  • ????????????
  • ???????????RNA ???????????

?????

  • MinION ??????????
  • Oxford Nanopore ?????????
  • ??????????? basecalling
  • ????????????????????
  • ??????????????????????

????

  • 2026-06-27 - 启动了带有门户网站布局的Nanopore Wiki主页，用于跟踪纳米孔技术、测序、工具和研究进展。

????

Nanopore Wiki ??????????????????????????????????????????????????????????????????

Site Notes

Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice.

References

Other languages:
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