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[[File:Nanopore_sequencing_principle.png|thumb|right|360px|Principle of nanopore sequencing. Source: Wikimedia Commons, DBCLS, CC BY 4.0.]]
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<div style="font-size:188%; line-height:1.2; margin-bottom:0.25em;">Welcome to Nanopore Wiki</div>
<div id="np-2012">
<div style="font-size:108%; max-width:58em;">A knowledge base and science outreach site for nanopore technology, nanopore sequencing, single-molecule sensing, bioinformatics workflows, instruments, and frontier research.</div>
<div id="np-2012-banner">
<div id="np-2012-banner-title">
<h1>Nanopore Wiki</h1>
<p>A rigorous, multilingual knowledge base for nanopore technology, sequencing, single-molecule sensing, and bioinformatics.</p>
</div>
</div>
<div id="np-2012-banner-intro">
<p>Start from concepts, follow reliable sources, and track frontier research.</p>
<table><tr><td>[[Nanopore technology|Technology]]</td><td>[[Nanopore sequencing|Sequencing]]</td><td>[[Bioinformatics|Bioinformatics]]</td></tr><tr><td>[[Glossary|Glossary]]</td><td>[[Latest Progress|Progress]]</td><td>[[Help:Contents|Help]]</td></tr></table>
</div>
</div>
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<div id="np-2012-body">
<div id="np-2012-column-left">
<div class="np-2012-block"><h2>Featured Topic</h2><div class="np-2012-text">
<div class="np-2012-image">[[File:Nanopore_sequencing_principle.png|frameless|220px|link=https://www.nanopore.net/index.php?curid=2|Principle of nanopore sequencing]]<div class="np-2012-caption">Principle of nanopore sequencing.</div></div>
Nanopores are nanoscale openings that allow ions or molecules to pass through a membrane or solid-state material. When a molecule moves through or near a nanopore, it can change an electrical current, ion flow, or another measurable signal. These signal changes can be used to study DNA, RNA, proteins, small molecules, and other biological or chemical systems at single-molecule scale.
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<div class="np-2012-block"><h2>Did You Know?</h2><div class="np-2012-text">
== Start Here ==
* Nanopore sequencing reads molecular signals directly as DNA or RNA passes through a nanoscale pore.
* [[Nanopore technology]]
* Long reads can help resolve repeats, structural variants, and complex genome regions.
* [[Nanopore sequencing]]
* Some nanopore methods can detect RNA or base modifications without converting molecules into short amplified fragments.
* [[Single-molecule detection]]
* Portable instruments make sequencing possible in field, classroom, clinical, and small-laboratory settings.
* [[Bioinformatics]]
</div></div>
* [[Glossary]]


Nanopores are nanoscale pores that can be used to observe molecules through changes in electrical current, ion flow, or other measurable signals. This makes them useful for sequencing, molecular sensing, and real-time analysis.
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<div class="np-2012-block"><h2>Picture of the Day</h2><div class="np-2012-text">
[[File:Nanopore_sequencing_principle.png|frameless|300px|center|link=https://www.nanopore.net/index.php?curid=2|Principle of nanopore sequencing]]
<div class="np-2012-caption">A schematic view of nanopore sequencing, where molecular movement through a pore is converted into measurable signal.</div>
</div></div>
</div>


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== Latest Progress ==
<div id="np-2012-column-right">
<div class="np-2012-block"><h2>News and Research Updates</h2><div class="np-2012-text">
{{:Latest Progress}}
{{:Latest Progress}}
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== Research Topics ==
<!--T:6-->
* [[Long-read sequencing]]
<div class="np-2012-block"><h2>Start Here</h2><div class="np-2012-text">
* [[Direct RNA sequencing]]
* [[Nanopore technology]] - principles, pore types, signals, and measurement concepts.
* [[Epigenetic modification detection]]
* [[Nanopore sequencing]] - how DNA and RNA sequencing with nanopores works.
* [[Pathogen detection]]
* [[Single-molecule detection]] - how nanopores can detect individual molecules.
* [[Environmental DNA]]
* [[Bioinformatics]] - basecalling, read mapping, assembly, variants, and quality control.
* [[Protein nanopore sensing]]
* [[Glossary]] - concise definitions of common terms.
</div></div>
 
<!--T:7-->
<div class="np-2012-block"><h2>Nanopore Wiki Reminds You</h2><div class="np-2012-text">
Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice. Claims about breakthroughs, clinical use, or product performance should be supported by reliable sources.
</div></div>
</div>
</div>


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== Tools and Workflows ==
<div id="np-2012-links">
* [[MinION]]
<table><tr>
* [[Oxford Nanopore]]
<td><h3>Knowledge Areas</h3>
* [[Basecalling]]
* [[Nanopore technology|Technology]]
* [[Read mapping]]
* [[Nanopore sequencing|Sequencing]]
* [[Variant calling]]
* [[Single-molecule detection|Single-molecule detection]]
* [[Genome assembly]]
</td>
* [[Quality control]]
<td><h3>Methods</h3>
|-
* [[Bioinformatics|Bioinformatics]]
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* [[MinION|Instruments]]
== Applications ==
* [[Oxford Nanopore|Platforms]]
* Public health surveillance
</td>
* Clinical and pathogen genomics
<td><h3>Community</h3>
* Agriculture and food safety
* [[Latest Progress|News and papers]]
* Environmental monitoring
* [[Help:Contents|Help]]
* Microbiome and metagenomics
* [[Nanopore Wiki:Editorial guidelines|Editorial guidelines]]
* Structural variant analysis
</td>
</tr></table>
</div>


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<!--T:9-->
== Contribute ==
<div id="np-2012-sisters">
Add new pages, improve definitions, summarize recent papers, and keep methods pages up to date. For new progress items, edit [[Latest Progress]] so the homepage updates automatically.
<p><b>Nanopore Wiki</b> is a knowledge and science-outreach project. The site can reserve space for related multilingual, open-content tasks and community-maintained resources:</p>
<table>
<tr><td class="np-sister-mark">G</td><td><b>[[Glossary|Glossary]]</b><br />Concise definitions for nanopore terms.</td><td class="np-sister-mark">N</td><td><b>[[Latest Progress|News and papers]]</b><br />Research updates, high-level papers, and technology progress.</td></tr>
<tr><td class="np-sister-mark">D</td><td><b>[[Bioinformatics|Data and bioinformatics]]</b><br />Workflows for signal, reads, mapping, assembly, and variants.</td><td class="np-sister-mark">I</td><td><b>[[MinION|Instruments and workflows]]</b><br />Portable sequencing devices and practical methods.</td></tr>
<tr><td class="np-sister-mark">H</td><td><b>[[Help:Contents|Help]]</b><br />How to read, search, and contribute.</td><td class="np-sister-mark">E</td><td><b>[[Nanopore Wiki:Editorial guidelines|Editorial guidelines]]</b><br />Quality standards for rigorous writing and sourcing.</td></tr>
</table>
</div>


<!--T:10-->
== References ==
== References ==
* [https://en.wikipedia.org/wiki/Nanopore Nanopore - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore Nanopore - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore_sequencing Nanopore sequencing - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore_sequencing Nanopore sequencing - Wikipedia]
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg Principle of nanopore sequencing - Wikimedia Commons]
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg Principle of nanopore sequencing - Wikimedia Commons]
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<languages />

Latest revision as of 11:47, 30 June 2026

Nanopore Wiki

A rigorous, multilingual knowledge base for nanopore technology, sequencing, single-molecule sensing, and bioinformatics.

Start from concepts, follow reliable sources, and track frontier research.

TechnologySequencingBioinformatics
GlossaryProgressHelp
Principle of nanopore sequencing
Principle of nanopore sequencing.

Nanopores are nanoscale openings that allow ions or molecules to pass through a membrane or solid-state material. When a molecule moves through or near a nanopore, it can change an electrical current, ion flow, or another measurable signal. These signal changes can be used to study DNA, RNA, proteins, small molecules, and other biological or chemical systems at single-molecule scale.

Did You Know?

  • Nanopore sequencing reads molecular signals directly as DNA or RNA passes through a nanoscale pore.
  • Long reads can help resolve repeats, structural variants, and complex genome regions.
  • Some nanopore methods can detect RNA or base modifications without converting molecules into short amplified fragments.
  • Portable instruments make sequencing possible in field, classroom, clinical, and small-laboratory settings.

Picture of the Day

Principle of nanopore sequencing
Principle of nanopore sequencing
A schematic view of nanopore sequencing, where molecular movement through a pore is converted into measurable signal.

News and Research Updates

  • 2026-06-27 - Nanopore Wiki homepage launched with a portal-style layout for tracking nanopore technology, sequencing, tools, and research progress.


Start Here

Nanopore Wiki Reminds You

Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice. Claims about breakthroughs, clinical use, or product performance should be supported by reliable sources.

Nanopore Wiki is a knowledge and science-outreach project. The site can reserve space for related multilingual, open-content tasks and community-maintained resources:

GGlossary
Concise definitions for nanopore terms.		NNews and papers
Research updates, high-level papers, and technology progress.
DData and bioinformatics
Workflows for signal, reads, mapping, assembly, and variants.		IInstruments and workflows
Portable sequencing devices and practical methods.
HHelp
How to read, search, and contribute.		EEditorial guidelines
Quality standards for rigorous writing and sourcing.

References

Other languages:
Retrieved from "https://wiki.nanopore.net/index.php?title=Main_Page&oldid=3086"