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<span id="Single-molecule_detection"></span>
= Single-molecule detection =
= 单分子检测 =
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<div lang="en" dir="ltr" class="mw-content-ltr">
'''单分子检测'''是指观察单个分子而不是仅测量整体平均值的方法。纳米孔对于单分子传感很有用,因为每个分子在与孔相互作用时可以产生独特的信号。
'''Single-molecule detection''' refers to methods that observe individual molecules rather than measuring only bulk averages. Nanopores are useful for single-molecule sensing because each molecule can produce a distinct signal while interacting with the pore.
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<div lang="en" dir="ltr" class="mw-content-ltr">
<span id="What_can_be_detected"></span>
== What can be detected ==
== 什么可以被检测到 ==
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<div lang="en" dir="ltr" class="mw-content-ltr">
* DNA和RNA分子。
* DNA and RNA molecules.
* 肽和蛋白质。
* Peptides and proteins.
* 小分子和代谢物。
* Small molecules and metabolites.
* 与疾病或环境监测相关的生物标志物。
* Biomarkers related to disease or environmental monitoring.
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<div lang="en" dir="ltr" class="mw-content-ltr">
<span id="Why_it_matters"></span>
== Why it matters ==
== 为什么它很重要 ==
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<div lang="en" dir="ltr" class="mw-content-ltr">
单分子方法可以揭示在集合测量中可能被隐藏的异质性、稀有事件、分子修饰和瞬时相互作用。
Single-molecule methods can reveal heterogeneity, rare events, molecular modifications, and transient interactions that may be hidden in ensemble measurements.
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<span id="Related_pages"></span>
== Related pages ==
== 相关页面 ==
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<div lang="en" dir="ltr" class="mw-content-ltr">
* [[Nanopore technology|Nanopore 技术]]
* [[Nanopore technology]]
* [[Nanopore sequencing|Nanopore 测序]]
* [[Nanopore sequencing]]
* [[Bioinformatics|生物信息学]]
* [[Bioinformatics]]
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Latest revision as of 13:55, 30 June 2026

单分子检测

单分子检测是指观察单个分子而不是仅测量整体平均值的方法。纳米孔对于单分子传感很有用,因为每个分子在与孔相互作用时可以产生独特的信号。

什么可以被检测到

  • DNA和RNA分子。
  • 肽和蛋白质。
  • 小分子和代谢物。
  • 与疾病或环境监测相关的生物标志物。

为什么它很重要

单分子方法可以揭示在集合测量中可能被隐藏的异质性、稀有事件、分子修饰和瞬时相互作用。

相关页面