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[[File:Nanopore_sequencing_principle.png|thumb|right|360px|link=https://www.nanopore.net/index.php?curid=2|Principle of nanopore sequencing. Source: Wikimedia Commons, DBCLS, CC BY 4.0.]]
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<div style="font-size:188%; line-height:1.2; margin-bottom:0.25em;">Welcome to Nanopore Wiki</div>
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<div style="font-size:108%; max-width:58em;">A knowledge base and science outreach site for nanopore technology, nanopore sequencing, single-molecule sensing, bioinformatics workflows, instruments, and frontier research.</div>
<h1>Nanopore Wiki</h1>
<p>A rigorous, multilingual knowledge base for nanopore technology, sequencing, single-molecule sensing, and bioinformatics.</p>
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<p>Start from concepts, follow reliable sources, and track frontier research.</p>
<table><tr><td>[[Nanopore technology|Technology]]</td><td>[[Nanopore sequencing|Sequencing]]</td><td>[[Bioinformatics|Bioinformatics]]</td></tr><tr><td>[[Glossary|Glossary]]</td><td>[[Latest Progress|Progress]]</td><td>[[Help:Contents|Help]]</td></tr></table>
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<div class="np-2012-block"><h2>Featured Topic</h2><div class="np-2012-text">
<div class="np-2012-image">[[File:Nanopore_sequencing_principle.png|frameless|220px|link=https://www.nanopore.net/index.php?curid=2|Principle of nanopore sequencing]]<div class="np-2012-caption">Principle of nanopore sequencing.</div></div>
Nanopores are nanoscale openings that allow ions or molecules to pass through a membrane or solid-state material. When a molecule moves through or near a nanopore, it can change an electrical current, ion flow, or another measurable signal. These signal changes can be used to study DNA, RNA, proteins, small molecules, and other biological or chemical systems at single-molecule scale.
Nanopores are nanoscale openings that allow ions or molecules to pass through a membrane or solid-state material. When a molecule moves through or near a nanopore, it can change an electrical current, ion flow, or another measurable signal. These signal changes can be used to study DNA, RNA, proteins, small molecules, and other biological or chemical systems at single-molecule scale.
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Nanopore methods matter because they can connect molecular events with real-time measurements. In sequencing, long DNA or RNA molecules pass through a pore and generate signals that can be converted into sequence information. In sensing, changes in current or other signals can reveal molecular size, charge, structure, binding, or chemical modification.
<div class="np-2012-block"><h2>Did You Know?</h2><div class="np-2012-text">
* Nanopore sequencing reads molecular signals directly as DNA or RNA passes through a nanoscale pore.
* Long reads can help resolve repeats, structural variants, and complex genome regions.
* Some nanopore methods can detect RNA or base modifications without converting molecules into short amplified fragments.
* Portable instruments make sequencing possible in field, classroom, clinical, and small-laboratory settings.
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[[File:Nanopore_sequencing_principle.png|frameless|300px|center|link=https://www.nanopore.net/index.php?curid=2|Principle of nanopore sequencing]]
== Start Here ==
<div class="np-2012-caption">A schematic view of nanopore sequencing, where molecular movement through a pore is converted into measurable signal.</div>
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<div class="np-2012-block"><h2>News and Research Updates</h2><div class="np-2012-text">
{{:Latest Progress}}
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<div class="np-2012-block"><h2>Start Here</h2><div class="np-2012-text">
* [[Nanopore technology]] - principles, pore types, signals, and measurement concepts.
* [[Nanopore technology]] - principles, pore types, signals, and measurement concepts.
* [[Nanopore sequencing]] - how DNA and RNA sequencing with nanopores works.
* [[Nanopore sequencing]] - how DNA and RNA sequencing with nanopores works.
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* [[Bioinformatics]] - basecalling, read mapping, assembly, variants, and quality control.
* [[Bioinformatics]] - basecalling, read mapping, assembly, variants, and quality control.
* [[Glossary]] - concise definitions of common terms.
* [[Glossary]] - concise definitions of common terms.
 
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== Why It Matters ==
* Long reads can span repeats, structural variants, and complex genomic regions.
* Real-time analysis can support rapid decisions in field, clinical, and laboratory settings.
* Portable instruments make sequencing and sensing possible outside large sequencing centers.
* Direct molecular measurements can preserve information about RNA, base modifications, or molecular context.
 
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== Applications ==
* Public health surveillance and pathogen genomics
* Clinical and infectious disease research
* Environmental DNA and biodiversity monitoring
* Microbiome and metagenomic analysis
* Agriculture, food safety, and biosecurity
* Structural variation, genome assembly, RNA analysis, and epigenetic modification detection


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<div class="np-2012-block"><h2>Nanopore Wiki Reminds You</h2><div class="np-2012-text">
== Tools and Workflows ==
Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice. Claims about breakthroughs, clinical use, or product performance should be supported by reliable sources.
* [[MinION]] and other portable sequencing instruments
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* [[Oxford Nanopore]] platforms and chemistry concepts
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* Basecalling from raw signal to sequence reads
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* Read mapping, variant calling, genome assembly, and quality control
* Experimental design, metadata, reproducibility, and responsible interpretation


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== Latest Progress ==
<td><h3>Knowledge Areas</h3>
{{:Latest Progress}}
* [[Nanopore technology|Technology]]
* [[Nanopore sequencing|Sequencing]]
* [[Single-molecule detection|Single-molecule detection]]
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<td><h3>Methods</h3>
* [[Bioinformatics|Bioinformatics]]
* [[MinION|Instruments]]
* [[Oxford Nanopore|Platforms]]
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<td><h3>Community</h3>
* [[Latest Progress|News and papers]]
* [[Help:Contents|Help]]
* [[Nanopore Wiki:Editorial guidelines|Editorial guidelines]]
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== Contribute ==
<p><b>Nanopore Wiki</b> is a knowledge and science-outreach project. The site can reserve space for related multilingual, open-content tasks and community-maintained resources:</p>
Nanopore Wiki welcomes careful contributions: clear definitions, reliable sources, reproducible methods, and balanced summaries of recent research. New progress items should include a date, a concise explanation, and a source when available.
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<tr><td class="np-sister-mark">G</td><td><b>[[Glossary|Glossary]]</b><br />Concise definitions for nanopore terms.</td><td class="np-sister-mark">N</td><td><b>[[Latest Progress|News and papers]]</b><br />Research updates, high-level papers, and technology progress.</td></tr>
<tr><td class="np-sister-mark">D</td><td><b>[[Bioinformatics|Data and bioinformatics]]</b><br />Workflows for signal, reads, mapping, assembly, and variants.</td><td class="np-sister-mark">I</td><td><b>[[MinION|Instruments and workflows]]</b><br />Portable sequencing devices and practical methods.</td></tr>
<tr><td class="np-sister-mark">H</td><td><b>[[Help:Contents|Help]]</b><br />How to read, search, and contribute.</td><td class="np-sister-mark">E</td><td><b>[[Nanopore Wiki:Editorial guidelines|Editorial guidelines]]</b><br />Quality standards for rigorous writing and sourcing.</td></tr>
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== Site Notes ==
Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice.
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== References ==
== References ==
* [https://en.wikipedia.org/wiki/Nanopore Nanopore - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore Nanopore - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore_sequencing Nanopore sequencing - Wikipedia]
* [https://en.wikipedia.org/wiki/Nanopore_sequencing Nanopore sequencing - Wikipedia]
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg Principle of nanopore sequencing - Wikimedia Commons]
* [https://commons.wikimedia.org/wiki/File:202001_nanopore_sequencing.svg Principle of nanopore sequencing - Wikimedia Commons]
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Latest revision as of 11:47, 30 June 2026

Nanopore Wiki

A rigorous, multilingual knowledge base for nanopore technology, sequencing, single-molecule sensing, and bioinformatics.

Start from concepts, follow reliable sources, and track frontier research.

TechnologySequencingBioinformatics
GlossaryProgressHelp
Principle of nanopore sequencing
Principle of nanopore sequencing.

Nanopores are nanoscale openings that allow ions or molecules to pass through a membrane or solid-state material. When a molecule moves through or near a nanopore, it can change an electrical current, ion flow, or another measurable signal. These signal changes can be used to study DNA, RNA, proteins, small molecules, and other biological or chemical systems at single-molecule scale.

Did You Know?

  • Nanopore sequencing reads molecular signals directly as DNA or RNA passes through a nanoscale pore.
  • Long reads can help resolve repeats, structural variants, and complex genome regions.
  • Some nanopore methods can detect RNA or base modifications without converting molecules into short amplified fragments.
  • Portable instruments make sequencing possible in field, classroom, clinical, and small-laboratory settings.

Picture of the Day

Principle of nanopore sequencing
Principle of nanopore sequencing
A schematic view of nanopore sequencing, where molecular movement through a pore is converted into measurable signal.

News and Research Updates

  • 2026-06-27 - Nanopore Wiki homepage launched with a portal-style layout for tracking nanopore technology, sequencing, tools, and research progress.


Start Here

Nanopore Wiki Reminds You

Nanopore Wiki is an educational and knowledge-organization project. Its pages are intended for science communication and general technical reference, and do not replace professional medical, legal, regulatory, or commercial advice. Claims about breakthroughs, clinical use, or product performance should be supported by reliable sources.

Nanopore Wiki is a knowledge and science-outreach project. The site can reserve space for related multilingual, open-content tasks and community-maintained resources:

GGlossary
Concise definitions for nanopore terms.		NNews and papers
Research updates, high-level papers, and technology progress.
DData and bioinformatics
Workflows for signal, reads, mapping, assembly, and variants.		IInstruments and workflows
Portable sequencing devices and practical methods.
HHelp
How to read, search, and contribute.		EEditorial guidelines
Quality standards for rigorous writing and sourcing.

References

Other languages:
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